Inhibition. Journal of Separation Science 2006 , 29 (14) , 2136-2142. Polygonum cuspidatum Sieb. Ganesh Jagetia, Sunil Krishnan Krishnan, Bharat B. Aggarwal. Paul W. Groundwater, Kevin R.H. Solomons, Jacqueline A. Drewe, Munawar Ali Munawar. [2] It is specifically isolated from Rheum Palmatum L.[3] It is also produced by many species of fungi, including members of the genera Aspergillus, Pyrenochaeta, and Pestalotiopsis, inter alia. Jen-Chung Ko, Ying-Jhen Su, Szu-Ting Lin, Jhih-Yuan Jhan, Shih-Ci Ciou, Chao-Min Cheng, Yu-Fan Chiu, Ya-Hsun Kuo, Min-Shao Tsai, Yun-Wei Lin. Although used for various applications, few clinical studies validate claims and guidance regarding dosing or safety is limited. This article is cited by First, it inhibits the motor activity of a parasitic Schistosoma species (Anantaphruti, et al, 1982). The International Journal of Biochemistry & Cell Biology. Abstract As part of effects to discover phytochemicals with melanin biosynthesis inhibitory activity, we screened emodin isolated from Polygonum multiflorum as a melanin biosynthesis inhibitor. The Replacement of ATP by the Competitive Inhibitor Emodin Induces Conformational Modifications in the Catalytic Site of Protein Kinase CK2. Competitive Price Emodin Polygonum Cuspidatum Extract Emodin Powder , Find Complete Details about Competitive Price Emodin Polygonum Cuspidatum Extract Emodin Powder,Emodin Polygonum Cuspidatum,Polygonum Cuspidatum Extract Emodin Powder,Emodin Powder from Supplier or Manufacturer-Xi'an Natural Field Bio-Technique Co., Ltd. Mei-Hwa Lee, Li Kao, and Chuan-Chuan Lin . Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. Polygonum extract herb health benefit by Ray Sahelian, M.D. P. cuspidatum contains flavones, such as resveratrol and emodin as the major chemical constituents (27,28). Reviewers, Librarians In China, there are about 80 species of used in]. Free radical scavenging activity and antiproliferative potential of Polygonum cuspidatum root extracts. In this study, emodin from Polygonum cuspidatum showed potent inhibitory effect against H. parasuis. In vitro inhibitory effects of Polygonum cuspidatum on bacterial viability and virulence factors of Streptococcus mutans and Streptococcus sobrinus. ; Oncogene 17, 913 (1998) NF-κB signaling pathway is associated with inflammatory responses and its inactivation may be critical for effective therapy of UC. Pao-Hsuan Huang, Chih-Yang Huang, Mei-Chih Chen, Yueh-Tsung Lee, Chia-Herng Yue, Hsin-Yi Wang, Ho Lin. Emodin is a polyphenol found in the roots, leaves, and bark of several plants, including aloe vera (Aloe barbadensis), cascara (Rhamnus pushiana), rhubarb (Rheum officinale), senna (Cassia angustifolia), Polygonum multiflorum, Polygonum cuspidatum, Psychotria camponutans, Radix et Rhizoma Rhei, Rheum palmatum, Stephania dinklagei, and Ventilago madraspatana. and subsequent isolation by semipreparative chromatography. Shih-Chang Chien, Yueh-Chen Wu, Zeng-Weng Chen, Wen-Chin Yang. First, it inhibits the motor activity of a parasitic Schistosoma species (Anantaphruti, et al, 1982). Structure Activity Relationship Study of Emodin Derivatives Based on the Protein-Tyrosine Kinase and Protein Kinase C Inhibitory Activities and Cytotoxicity. Negative-ion fast atom bombardment and tandem mass spectrometric investigation of phenylpropanoid glycosides isolated fromPolygonum pensylvanicum L.. Young Ho Kim, Eung-Seok Lee, Nuphavan M. Koonchanok, Robert L. Geahlen, Curtis L. Ashendel, Ching-Jer Chang. Polygonum cuspidatumの地下茎の抽出物が含有するATP低下作用を持つ成 分の定。 2-3. emodinがin vitro、in vivoにおいてB16F10細胞の増殖に及ぼす影響。 2-4. emodinがミトコンドリアの機能に与える作 … Yong-Suk Kim, Cheol-Seung Hwang, Dong-Hwa Shin. Protein Kinase C Inhibitory Phenylpropanoid Glycosides from Polygonum Species. 55, 696 (1992) Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells: A. Kumar, et al. Junko Koyama, Atsuko Takeuchi, Izumi Morita, Yu Nishino, Maki Shimizu, Munetaka Inoue, Norihiro Kobayashi. The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia. 抗菌性 イタドリ Polygonum cuspidatum extracts (H2O) ↑ 5. isolated and structurally identified as physcion (1) and emodin (2) from the alcoholic extract of the root of Polygonum cuspidatum. F. von Bruchhausen, G. Dannhardt, S. Ebel, A. W. Frahm, E. Hackenthal, R. Hänsel, U. Holzgrabe, K. Keller, E. Nürnberg, H. Rimpler, G. Schneider, P. Surmann, H. U. Wolf, G. Wurm, R. D. Aye, G. Bader, I. Bauer, R. Bauer, H. Becker, G. Beyer, W. Blaschek, N. Brand, U. Braun-Sprakties, R. Brenneisen, R. Broese, A. Burger, J. Burghart, N. Chaurasia, W. Cholcha, U. Eilert, D. Ennet, W. Ferstl, E. Fiegert, F. Gaedcke, B. Gehrmann, K. Gomaa, P. Gorecki, M. W. Grubert, G. Harnischfeger, H. J. Helmlin, G. Henkler, A. Hensel, G. Heubl, A. Hiermann, K. Hiller, K. Hoffmann-Bohm, B. Hohmann, W. Holz, J. Hölzl, K. H. Horz, O. Isaac, C. Jerga, W. Juretzek, T. Kartnig, H. P. Koch, H. Koehler, L. Kraus, W. Kreis, E. Leng-Peschlow, R. Liersch, U. Lindequist, E. Mechler, B. Meier, M. Meier-Liebi, H. G. Menßen, I. Merfort, H. Miething, S. Moeck, S. Mundt, K. Münzing-Vasirian, S. Noster, N. Ohem, D. Paper, J. Reichling, W. Schilz, H. Schleinitz, E. Schneider, E. Scholz, T. Schöpke, V. Schulz, H. Schütt, H. Schwarze, S. Schweins, B. Schwell, R. Seitz, U. Sonnenborn, E. Spieß, V. Ssymank, K. Staesche, E. Stahl-Biskup, H. Stuppner, E. Teuscher, M. Veit, A. Wiebrecht, M. Wink, U. Wissinger-Gräfenhahn, R. Wohlfart, B. Zepernick. The protein kinase 2 inhibitor tetrabromobenzotriazole protects against renal ischemia reperfusion injury. Emodin inhibits TNF α-induced MMP-1 expression through suppression of activator protein-1 (AP-1). Emodin-induced muscle contraction of mouse diaphragm and the involvement of Ca Alexander D. Crawford, Sandra Liekens, Appolinary R. Kamuhabwa, Jan Maes, Sebastian Munck, Roger Busson, Jef Rozenski, Camila V. Esguerra, Peter A. M. de Witte, . It is a member of the genus Polygonum in the family Polygonaceae, which grows in Asia and North America. Prenylated Flavanones from Secondary metabolites from species of the biocontrol agent Trichoderma. You’ve supercharged your research process with ACS and Mendeley! Emodin may also be used in conjunction with known antischistosomal drugs. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. อะไร Polygonum Cuspidatum สารสก ดจาก Polygonum cuspidatum ดอกไม ม ลค าโดยผ งเป นแหล งสำค ญน ำท พย ผ ง, ในช วงเวลาป เม อเล กๆน อยๆคนอ นๆค อการออกดอก Polygonum cuspidatum อาหารถ กใช … Emodin and physcion are abundant anthraquinone Sun-O Ka, Hong Pil Hwang, Jong-Hwa Jang, In Hyuk Bang, Ui-Jin Bae, Hee Chul Yu, Baik Hwan Cho, Byung-Hyun Park. The common name is derived from Rheum emodi, a taxonomic synonym of Rheum australe, (Himalayan rhubarb) and synonyms include emodol, frangula emodin, rheum emodin, 3-methyl-1,6,8-trihydroxyanthraquinone, Schuttgelb, and Persian Berry Lake. La pianta è dotata di fusti vigorosi e glabri, che possono raggiungere un' altezza massima di 3-4 metri. Your Mendeley pairing has expired. 55, 696 (1992) Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells: A. Kumar, et al. Hee-Jin Kwak, Myung-Jin Park, Chang-Min Park, Sang-Ik Moon, Doo-Hyun Yoo, Hyung-Chahn Lee, Seung-Hoon Lee, Mi-Suk Kim, Hyean-Woo Lee, Woon-Seob Shin, In-Chul Park, Chang Hun Rhee, Seok-Il Hong. The amounts of emodin, resveratrol and polydatin in Polygonum cuspidatum, as estimated by the proposed method, were 4.96 mg g–1, 1.81 mg g–1, … It is a member of the genus Polygonum in the family Polygonaceae, which grows in Asia and North America. In the present study, the possibility of using emodin as a potential antiviral to treat CVB 4 infection was explored in vitro and in mice. Acta Crystallographica Section D Structural Biology. (A) Polygonum cuspidatum (PC), resveratrol, and emodin reduced plaque numbers in a plaque reduction assay. Evolution of Antimicrobial, Antioxidant Potentials and Phytochemical Studies of Three Solvent Extracts of Five Species from Acacia Used in Sudanese Ethnomedicine. Mechanisms of drug combinations: interaction and network perspectives. Polygonum cuspidatum is a herbal medicine commonly used for the treatment of atherosclerosis, as well as other medical ailments including cancers, asthma, … Polygonum cuspidatum extracts (H2O) emodin Polygonum cuspidatum S crude extracts ↑ 4. Polygonum cuspidatum (PC), resveratrol, and emodin reduced plaque numbers in a plaque reduction assay and inhibited the accumulation of hemagglutinin and neuraminidase in A549 cells. Chemical structures of these isolates were identified by interpretation of spectroscopic data ( 1 H, 13 C NMR Structural and thermodynamic analyses of interactions between death-associated protein kinase 1 and anthraquinones. Emodin is a polyphenol found in the roots, leaves, and bark of several plants, including aloe vera (Aloe barbadensis), cascara (Rhamnus pushiana), rhubarb (Rheum officinale), senna (Cassia angustifolia), Polygonum multiflorum, Polygonum cuspidatum, Psychotria camponutans, Radix et Rhizoma Rhei, Rheum palmatum, Stephania dinklagei, and Ventilago madraspatana.Di 2015, Han 2015, Jia 2014, Lee 2011, Lin 2015, Nemmar 2015, Sharma 2017, Xue 2015 Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation. A facile synthesis of emodin derivatives, emodin carbaldehyde, citreorosein, and their 10-deoxygenated derivatives and their inhibitory activities on μ-calpain. Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-κB. Antioxidant and anti-inflammatory flavonol glucuronides from Polygonum aviculare L.. N. N. Gessler, A. S. Egorova, T. A. Belozerskaya. The methanolic extract of P. cuspidatum root contains anthraglycoside B, physcion, piceid, emodin and resveratrol [ 22 ] . Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. Jing Lu Liang, Hyo Chang Cha, Seung Ho Lee, Jong-Keun Son, Hyeun Wook Chang, Ji-Eun Eom, Youngjoo Kwon, Yurngdong Jahng. Resveratrol is a natural antioxidant polyphenol that is present in P. cuspidatum , which exerts various biological functions, including anti-inflammatory and antioxidant activities ( 40 , 41 ). Hong-Mei Lu, Wang-Dong Ni, Yi-Zeng Liang, Rui-Lin Man. Polygonum cuspidatum). European Journal of Clinical Investigation. Harpreet Singh, Piyush Chahal, Amrita Mishra, Arun Kumar Mishra. P. cuspidatum Siebold & Zucc. Roberto Battistutta, Erika De Moliner, Stefania Sarno, Giuseppe Zanotti, Lorenzo A. Pinna. Polygonum cuspidatum). Physcion and physcion 8-O-β-glucopyranoside: A review of their pharmacology, toxicities and pharmacokinetics. Polygonum cuspidatum Japanese Knotweed This plant is native to Eastern Japan, China and Korea. Herb medicine Inchin-ko-to (TJ-135) regulates PDGF-BB-dependent signaling pathways of hepatic stellate cells in primary culture and attenuates development of liver fibrosis induced by thioacetamide administration in rats. Kazumasa Ohashi, Kaori Sampei, Mami Nakagawa, Naoto Uchiumi, Tatsuya Amanuma, Setsuya Aiba, Masato Oikawa, Kensaku Mizuno, . influx and Ca Resveratrol is a natural antioxidant polyphenol that is present in P. cuspidatum , which exerts various biological functions, including anti-inflammatory and antioxidant activities ( 40 , 41 ). Ling Zhang, Dian He, Kun Li, Hongli Liu, Baitao Wang, Lifang Zheng, Jiazhong Li. J.C. Chukwujekwu, P.H. Emodin Regulates Apoptotic Pathway in Human Liver Cancer Cells. Tao Luo, Na Li, Yuan-qiao He, Shi-qi Weng, Tao Wang, Qian-xing Zou, Xu-hui Zeng. Emodin isolated from Polygoni Multiflori Ramulus inhibits melanogenesis through the liver X receptor-mediated pathway. Silk fibroin mediated delivery of liposomal emodin to breast cancer cells. Yukihiro Imanishi, Naoto Maeda, Kohji Otogawa, Shuichi Seki, Hiroko Matsui, Norifumi Kawada, Tetsuo Arakawa. Librarians & Account Managers. Antonio R. da Cunha, Evandro L. Duarte, Hubert Stassen, M. Teresa Lamy, Kaline Coutinho. Pharmacokinetics and tissue distribution of resveratrol, emodin and their metabolites after intake of Polygonum cuspidatum in rats. In the United States it is considered an invasive species as it is in most other countries. Jongsung Lee, Eunsun Jung, Jiyoung Lee, Sungran Huh, Cheng-Hwan Hwang, Hwa-Young Lee, Eun-Jung Kim, Ji-Min Cheon, Chang Gu Hyun, Yeong Shik Kim, Deokhoon Park. is a natural plant that is widely distributed in China and Japan, and it is used in traditional Chinese herbal medicine. Find more information about Crossref citation counts. Roland Reinehr, Stephan Becker, Matthias Wettstein, Dieter Häussinger. Emodin dose-dependently inhibited the level of melanin biosynthesis in B16 melanoma cells, with little cytotox- icity at the effective concentrations. Preparation of Emodin-Polyethylene Glycol Composite Microparticles Using a Supercritical Antisolvent Process. BioPure Japanese Knotweed from Polygonum cuspidatum, also known as Japanese Knotweed, or by the Mandarin Chinese name of Hu Zhang, is native to Asia, and is a robust perennial in the Buckwheat family. Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum: H. Jayasuriya, et al. 112 publications. is rich with phenolics and has been used for the treatments of amenorrhea, arthralgia, jaundice, abscess, scald, and … Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is one of the natural anthraquinone derivatives obtained from the root and rhizome of Polygonum cuspidatum. Japon Madımağı veya Polygonum Cuspidatum, dolaşım sistemi ve kalp sağlığı için kullanılan Geleneksel Çin Tıbbıdır. Yue Lu, Ju Hye Yang, Xian Li, Kyoung Hwangbo, Seung-Lark Hwang, Yoshitaka Taketomi, Makoto Murakami, Young-Chae Chang, Cheorl-Ho Kim, Jong-Keun Son, Hyeun Wook Chang. Salvador Máñez, María Del Carmen Recio. Comparison of the Antioxidant and Transmembrane Permeative Activities of the Different Polygonum cuspidatum Extracts in Phospholipid-Based Microemulsions. Feasibility Evaluation of Emodin (Rhubarb Extract) as an Inhibitor of Pancreatic Cancer Cell Proliferation In Vitro. Find more information about Crossref citation counts. et Zucc. 細胞毒性 イタドリ emodin ↑ 6. via Polygonum cuspidatum Japanese Knotweed This plant is native to Eastern Japan, China and Korea. Simple Flavones Possessing Complex Biological Activity. Hitoshi Nagashima, Kumiko Nakamura, Tetsuhisa Goto. P. cuspidatum also produces emodin, an anthraquinone, that has several effects. Gopal Srinivas, Suboj Babykutty, Priya Prasanna Sathiadevan, Priya Srinivas. Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is a chemical compound that can be isolated from rhubarb, buckthorn, and Japanese knotweed (Reynoutria japonica syn. Antithrombotic Effect and Antiplatelet Activity of Polygonum cuspidatum Extract. M. Mizuno, H. Kawamura, N. Takei, H. Nawa. BIOLOGICALLY ACTIVE COMPOUNDS OF KNOTWEED (Reynoutria spp.). Resveratrol and emodin Evidence-Based Complementary and Alternative Medicine. Characterization of emodin metabolites in Raji cells by LC–APCI-MS/MS. Emodin - a secondary metabolite with multiple ecological functions in higher plants. Polygoni Cuspidati Radix Inhibits the Activation of Syk Kinase in Mast Cells for Antiallergic Activity. Citations are the number of other articles citing this article, calculated by Crossref and updated daily. 細胞毒性 イタドリ emodin ↑ 6. The Construction of Polysubstituted Aromatic Core Derivatives Inhibition of DNA topoisomerases I and II of compounds from Reynoutria japonica. Micronization of the officinal component emodin via the SEDS process through prefilming atomization. Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum: H. Jayasuriya, et al. 518-82-1 Chemical Name: 1,3,8-Trihydroxy-6-methylanthraquinone Other Extract origins: Rheum palmatum Rheum palmatum L roots Appearance: Orange needle crystal powder Specification: 10%~98% HPLC Molecular … Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta. Differentiation of Rhizoma Et Radix Polygoni Cuspidati from Closely Related Herbs by HPLC Fingerprinting. Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes. It is specifically isolated from Rheum Palmatum L. [3] It is also produced by many species of fungi, including members of the genera Aspergillus , Pyrenochaeta , and Pestalotiopsis , inter alia. In the present study, the possibility of using emodin as a potential antiviral to treat CVB 4 infection was explored in vitro and in mice. Polygonum cuspidatum extracts (H2O) emodin Polygonum cuspidatum S crude extracts ↑ 4. Pharmacokinetics and tissue distribution of resveratrol, emodin and their metabolites after intake of Polygonum cuspidatum in rats. is rich with phenolics and has been used for the treatments of amenorrhea, arthralgia, jaundice, abscess, scald, and … Emodin targets mitochondrial cyclophilin D to induce apoptosis in HepG2 cells. 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Introduction Emodin (1,3,8‐trihydroxy‐6‐methylanthraquinone) (Fig. Shahzad A. Pandith, Riyaz Ahmad Dar, Surrinder K. Lattoo, Manzoor A. Shah, Zafar A. Reshi. Preparation, characterization and in vitro anticoagulation of emodin-eluting controlled biodegradable stent coatings. How to Polygonum Cuspidatum Extract Actions in pharmacological Composition analysis of Knotweed reveals it to be a vessel for resveratrol (as well as a few other compounds structurally similar to resveratrol and may act in the same way) and Rheum emodin .Both 脂質低下 [ 1 ] [ 2 ] イタドリ piceid resveratrol ↑ The anthraquinone emodin inhibits the non-exported FIKK kinase from Plasmodium falciparum. In lieu of an abstract, this is the article's first page. Ultrasonic-Assisted Extraction of the Botanical Dietary Supplement Resveratrol and Other Constituents of Polygonum cuspidatum. Jiří Patočka, Zdeňka Navrátilová, Maribel Ovando. Lin SP, Chu PM, Tsai SY, Wu MH, Hou YC. α-Synuclein Aggregation and Ser-129 Phosphorylation-dependent Cell Death in Oligodendroglial Cells. Zhifen Chen, Lu Zhang, Junyang Yi, Zhuanbo Yang, Zhijie Zhang, Zhen Li. In this study, emodin from Polygonum cuspidatum showed potent inhibitory effect against H. parasuis. Polygonum Cuspidatum Extract Emodin10%~98% HPLC Botanical name: Polygonum Cuspidatum Synonym name: Frangula emodin, Rheum emodin, Archin CAS NO. Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: A study on its mechanism of action. Eight active compounds have been identified from PC extract: 2-methoxystypandrone (1); emodin (2 et Zucc., a well-known traditional Chinese medicine and officially listed in the Chinese Pharmacopoeia, has been traditionally used for treatment of various inflammatory diseases, hepatitis, tumors, and diarrhea in East … Constituents from Polygonum cuspidatum Kai X IAO , 1) Lijiang X UAN , Yaming X U ,* Donglu B AI , and Dexin Z HONG Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; 294 Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is a chemical compound that can be isolated from rhubarb, buckthorn, and Japanese knotweed (Reynoutria japonica syn. Anthraquinones from the saline-alkali plant endophytic fungus Eurotium rubrum. Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9. Optimization and validation of a chromatographic method for the simultaneous quantification of six bioactive compounds in Rhizoma et Radix Polygoni Cuspidati. FIKK Kinase, a Ser/Thr Kinase Important to Malaria Parasites, Is Inhibited by Tyrosine Kinase Inhibitors. Den-En Shieh, Yuan-Ying Chen, Ming-Hong Yen, Lien-Chai Chiang, Chun-Ching Lin. Hitoshi NAGASHIMA, Kumiko NAKAMURA, Tetsuhisa GOTO. Zebrafish Bioassay-Guided Natural Product Discovery: Isolation of Angiogenesis Inhibitors from East African Medicinal Plants. Antibacterial, high-flux and 3D porous molecularly imprinted nanocomposite sponge membranes for cross-flow filtration of emodin from analogues. Investigation of the interactive effects between emodin and genistein in rat vascular smooth muscle cell line A-10. release from sarcoplasmic reticulum. Emodin, an antibacterial anthraquinone from the roots of Cassia occidentalis. (PCS) has antibacterial properties and may prevent Ulcerative colitis (UC) but related molecular mechanism remains unknown. Note: Benjamin C. Lin, Darcy R. Harris, Lucy M.D. Polygonum cuspidatum extract was administered orally, it had obvious inhibitory effects on mice with Ehrlich ascites carcinoma, sarcoma carcinoma 180, liver cancer, breast cancer, lymphosarcoma, melanoma, and Wacker carcinoma of rats. Fen Hu, Donglan Zhu, Weiwei Pei, Imshik Lee, Xinzheng Zhang, Leiting Pan, Jingjun Xu. Proteome scale census of major facilitator superfamily transporters in Trichoderma reesei using protein sequence and structure based classification enhanced ranking. La pianta è dotata di fusti vigorosi e glabri, che possono raggiungere un' altezza massima di 3-4 metri. ; J. Nat. Yann-Lii Leu, Tsong-Long Hwang, Jiuan-Wen Hu, Jia-You Fang. Experimental and theoretical studies of emodin interacting with a lipid bilayer of DMPC. A representative plaque reduction assay is shown. Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells. is a herbaceous perennial plant. A tumor cell growth inhibitor from polygonum hypoleucum Ohwi. It has various actions including laxative, antibacterial and antiinflammatory effects,[5][6] and has also been identified as having potential antiviral activity against coronaviruses such as SARS-CoV-2,[7][8] being one of the major active components of the antiviral TCM formulation Lianhua Qingwen.[9][10]. Polygonum cuspidatum Sieb. Guangsheng Qian, Sik-Yuen Leung, GuangHua Lu, Kelvin Sze-Yin Leung. Bao-Yuan Chen, Chia-Hung Kuo, Yung-Chuan Liu, Li-Yi Ye, Jiann-Hwa Chen, and Chwen-Jen Shieh . Polygonum cuspidatum Siebold & Zucc. Surface-enhanced Raman spectroscopy study of the interaction of the antitumoral drug emodin with human serum albumin. Roberto Battistutta, Stefania Sarno, Erika De Moliner, Elena Papinutto, Giuseppe Zanotti, Lorenzo A. Pinna. Yonghong Zhang, Lanlan Zheng, Yan Zheng, Chao Zhou, Ping Huang, Xiao Xiao, Yongheng Zhao, Xincai Hao, Zhubing Hu, Qinhua Chen, Hongliang Li, Xuanbin Wang, Kenji Fukushima, Guodong Wang, Chen Li. Polygonum cuspidatum (PC), commonly called Japanese knotweed, is a member of the buckwheat family (Polygonaceae). Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Please note: If you switch to a different device, you may be asked to login again with only your ACS ID. ; Oncogene 17, 913 (1998) Christine L. Kragh, Louise B. Lund, Fabia Febbraro, Hanne D. Hansen, Wei-Ping Gai, Omar El-Agnaf, Christiane Richter-Landsberg, Poul Henning Jensen. Roland Reinehr, Stephan Becker, Andrea Höngen, Dieter Haüssinger. NF-κB signaling pathway is associated with inflammatory responses and its inactivation may be critical for effective therapy of UC. Yonggang Zhang, Airong Jia, Huabin Chen, Menghua Wang, Gang Ding, Liyan Sun, Li Li, Meixue Dai. Kyoung Hwangbo, Ming Shan Zheng, Young-Jin Kim, Jong-Yeop Im, Chong-Soon Lee, Mi-Hee Woo, Yurngdong Jahng, Hyun-Wook Chang, Jong-Keun Son. Mark Petrash . Takeuchi, Izumi Morita, Yu Zong Chen carbaldehyde, citreorosein, polygonum cuspidatum emodin Japanese knotweed ( japonica... Few clinical studies validate claims and guidance regarding dosing or safety is limited Aiba... Quan ling Suo, Zhong Min Lang, H. L. Hong, Quan ling Suo, Min. Cuspidatum, dolaşım sistemi ve kalp sağlığı için kullanılan Geleneksel Çin Tıbbıdır alla famiglia delle Polygonaceae by. In profondità, emodin and physcion from Polygonum cuspidatum S crude extracts ↑ 4 other constituents of cuspidatum! The interactive effects between emodin and resveratrol [ 22 ] Ahmad Dar Surrinder... Potential anticancer Leads Inspired by natural Products a reactive oxygen species-dependent mitochondrial signaling is. Tricia A. Babcock, Scott Helton polygonum cuspidatum emodin N. Joseph Espat Yokoyama, Peter Wijaya Yuto... Anticancer Leads Inspired by natural Products Derived from Polygonum cuspidatum ( PC ), resveratrol, emodin from cuspidatum! イタドリ Polygonum cuspidatum extracts in Phospholipid-Based Microemulsions root 【基原】タデ科のイタドリの根茎。 【薬能・薬理作用】 アントラキノン・アントラキノン配糖体・フラボン配糖体・タンニン・多糖などを含む。がん抑制物質であるリスベラトロールを含む。 Although antibiotics widely. Damnacanthal, an anthraquinone, that has become popular since it is a natural plant that widely! Updated daily by reducing sperm [ Ca2+ ] i and II of compounds from Reynoutria syn... Method for the conversion of cortisone into cortisol, Yuan-qiao He, Shi-qi Weng, tao Wang, Ding! Monika E. Czerwińska, Barbara Guerra Tsai SY, Wu MH, Hou YC extracts ↑ 4 rat... Çok iyi bir kaynaktır ve Polygonum polygonum cuspidatum emodin is an herb that has become popular since it considered... 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